Current Issue : October - December Volume : 2020 Issue Number : 4 Articles : 6 Articles
Background. Vitiligo is not a well-studied disease in Ethiopia. Therefore, this study assessed its clinico-epidemiological profile and\ntreatment patterns. Methods. An institutional-based cross-sectional study was conducted in conveniently selected dermatologic\nclinics of Mekelle city, Ethiopia. A two-phased study was conducted, in which the first was to determine prevalence of vitiligo\nwhile the second phase was to describe the clinico-epidemiological profile and treatment pattern of vitiligo. Four-hundred three\nrandomly selected dermatological patients were included in the first phase study. The second phase study included vitiligo cases\nfrom the first phase study and additional vitiligo cases found in a two months period prospective study. Results. Of the 403\nrandomly selected dermatological patients who presented in the year 2017 to 2019, the prevalence of vitiligo was 13.15%. Of the 79\ncases with vitiligo, nearly two-thirds................
Having psoriasis in hard-to-treat areas, i.e. the scalp, face, palms, soles, nails, and genitals, respectively,\ncan impair patientsâ?? quality of life. We investigated the prevalence of hard-to-treat body locations of psoriasis, and\ndescribed patientsâ?? clinical and demographic characteristics, and quality of life impacts in a population-based\ncohort..........................
Psoriasis and psoriatic arthritis are chronic, relapsing, immune-based diseases. Psoriatic patients may have nail involvement in 50\nto 80% of cases, and this may reach 85% in patients with joint disease, in spite of the fact that the relationship between psoriasis and\nonychomycosis is not well established. The aim of this study was to investigate the occurrence of onychomycosis in patients with\nnail disorders and diagnosis of psoriasis and psoriatic arthritis. This was a cross-sectional study in which 38 patients diagnosed\nwith psoriasis and/or psoriatic arthritis were interviewed and had altered nail samples analysed by mycological and histopathological\nexams. Twenty-two (57.89%) patients had a confirmed diagnosis for onychomycosis. Seventeen (44.8%) had a\npositive direct mycological examination, 16 (42.1%) had positive cultures, and 12 (31.6%) were positive for fungi by histopathological\nexamination. Dermatophytes were identified in nine (56.3%) cultures, and of these, eight were Trichophyton rubrum\nand one T. tonsurans. Yeasts were isolated in seven patients (43.75%), which included four Candida parapsilosis and three C.\nalbicans. Six patients (15.78%) were not using immunosuppressive therapy, and the others were using methotrexate, etanercept,\nadalimumab, infliximab, secukinumab, or golimumab, in monotherapy or in combination with other drugs. The confirmed\nonychomycosis rate in patients using methotrexate alone was 92.8% (n = 13). We concluded that it is possible that there is a\npositive relationship between psoriatic disease and onychomycosis. And we highlight that it is also worth investigating in the\nfuture the possible role of immunosuppressive therapy (mainly methotrexate) as a predisposing factor for the development of\nfungal infections in psoriatic patients....
The overall well-being, sense of stigmatization, and treatment outcome of persons with vitiligo are largely dependent\non their social acceptance and this is linked with perception and attitude of this disease in a given population. Therefore, this study\nassessed the knowledge and attitude of the public towards vitiligo. Methods. A cross-sectional survey was carried out using a selfreported\nquestionnaire distributed to adults living in Mekelle city, Northern Ethiopia from August to November 2019. Individuals\nwho were 18 to 65 years of age and not suffering from vitiligo were included in the study. A self-administered questionnaire that\ncontains a demographic, knowledge, and attitudes parts was used to collect data. Data were entered using Epi............................
Introduction: Split thickness skin grafts are frequently employed to provide\nbiological cover for extensive wounds. The take of the skin graft is traditionally\nestimated by observation and recorded as a percentage. The intent of this\nstudy was to ascertain the reliability of the observation method in comparison\nwith the Image J digital programme. Materials and Methods: The study was\na longitudinal study conducted on the wards of the National Reconstructive\nPlastic Surgery and Burns Centre (NRPSBC) at the Korle Bu Teaching Hospital\n(KBTH) on patients who were admitted during the period of the study\nwith wounds who received split skin grafts. Image................
Uses of general anaesthesia in outpatient invasive procedures have increased, especially in dermatology. Being\nuncooperative, children often require general anaesthesia, since surgical skin operations are mostly painful. Aim. The purpose of\nthis study is to evaluate the safety, significant adverse events, and the complication rates related to general anaesthesia, when used\namong pediatric population undergoing skin procedures. Methods. We conducted a first retrospective cohort study of patient\nchart review during the period from September 1, 2017 through September 2019. All patients admitted for pediatric skin\nprocedures during this period have participated in our study. We reviewed selected charts to document any unexpected admissions,\nadverse events, or complications. Surgical outcomes and anaesthesia complications were reviewed by three anesthesiologists.\nWe assessed inter-rater reliability. Results. A total of 211 procedures were reported for 211 patients with 19 diagnoses.\nNo adverse events related to anaesthesia were recognized, apart from minor complications noticed in twelve patients. The kappa\nvalue range is between 0.78 and 1.00 (95% C.I., 0.46809 to 1.00). Conclusion. Dermatologist and pediatricians can safely do\nnecessary procedures under general anaesthesia with the supervision of pediatric-trained anesthesiologists while considering\nother safety and risk precautions and the pediatric age group....
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